diffuse hyperpigmented subcutaneous nodules as a primary manifestation of disseminated bacillus calmette-guerin disease in young infants

نویسندگان

sedigheh rafiei tabatabaei pediatric infections research center, mofid children’s hospital, shahid beheshti university of medical sciences, tehran, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

ali amanati professor alborzi clinical microbiology research center, shiraz university of medical sciences, shiraz, ir iran; professor alborzi clinical microbiology research center, shiraz university of medical sciences, shiraz, iran, amir oncology hospital; address: fars - shiraz - farhang shahr - against kosar pool, fax: +98-7136325655, postal code: +98-7187915998سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (shiraz university of medical sciences)

abdollah karimi pediatric infections research center, mofid children’s hospital, shahid beheshti university of medical sciences, tehran, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

kourosh goudarzipour pediatric congenital hemathologic disorders research center, shahid beheshti university of medical sciences, tehran, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

چکیده

conclusions subcutaneous nodules in the absence of a local reaction at the site of bcg vaccination may be the sole manifestation of disseminated bcg disease. case presentation we report on an 11-months-old boy with prolonged fever and diffuse hyperpigmented subcutaneous nodules. due to lymphopenia, oral thrush and severe adverse reaction to bcg vaccination, the possibility of primary immunodeficiency was considered for him and immunological investigations were done. introduction there are increasing reports of serious adverse events of bacillus calmette-guerin (bcg) vaccination in infants with unrecognized primary immunodeficiency disorders (pids) in our country. among these adverse events skin manifestations occur less frequently and are less noticed.

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عنوان ژورنال:
archives of pediatric infectious diseases

جلد ۳، شماره ۴، صفحات ۰-۰

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